Ewing sarcoma/primitive neuroectodermal tumor of the kidney treated with chemotherapy including ifosfamide

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• 作者：Hiroki Yoshihara ; Takahiro Kamiya ; Yosuke Hosoya ; Daisuke Hasegawa ; Chitose Ogawa ; Hiroshi Asanuma ; Ryuichi Mizuno ; Ryota Hosoya and Atsushi Manabe
• 刊名：Pediatrics International
• 出版年：2016
• 出版时间：August 2016
• 年：2016
• 卷：58
• 期：8
• 页码：766-769
• 全文大小：350K
• ISSN：1442-200X

文摘

Ewing sarcoma/primitive neuroectodermal tumor (ES/PNET) of the kidney is extremely rare, and is usually diagnosed after nephrectomy without neoadjuvant chemotherapy. Although ifosfamide and etoposide improve survival to a great extent in ES/PNET, the use of nephrotoxic agent, particularly ifosfamide, is a concern after nephrectomy. We describe the case of a 14-year-old female patient with abdominal mass who was diagnosed with ES/PNET of the right kidney after nephrectomy. Adjuvant chemotherapy including ifosfamide and etoposide were given. The estimated glomerular filtration rate decreased to 75% after the end of therapy. There was no evidence of recurrence 70 months after initial diagnosis.