Urinary heme oxygenase-1 as a potential biomarker for early diabetic nephropathy

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• 作者：Zhenzhen Li ; Yuliang Xu ; Xianghua Liu ; Yali Nie and Zhanzheng Zhao
• 刊名：Nephrology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：22
• 期：1
• 页码：58-64
• 全文大小：250K
• ISSN：1440-1797

文摘

Our previous study showed that increases of urinary heme oxygenase-1 (uHO-1) could be a potential biomarker indicating evaluating intrarenal oxidative damage in obstructive nephropathy. Activation of oxidative stress is an important mediator of diabetic nephropathy (DN). The aim of this study was to investigate the clinical implications of uHO-1 levels in patients with type 2 diabetes.