ChemInform Abstract: Stereoselective Synthesis of trans-Perfluoroalkylated [1,3]Oxazino[2,3-a]isoquinolines from Aromatic Aldehydes, Methyl Perfluoroalk-2-ynoates and Isoquinolines.
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- 作者：Zhiliang Xu ; Tianqi Sun ; Qiuqi Cai ; Fei Ni ; Jing Han ; Jie Chen ; Hongmei Deng ; Min Shao ; Hui Zhang and Weiguo Cao
- 关键词：oxazine derivatives ; multicomponent reactions ; diastereoselective syntheses ; enantioselective syntheses (incl. cis/trans-isomerism)
- 刊名：ChemInform
- 出版年：2016
- 出版时间：April, 2016
- 年：2016
- 卷：47
- 期：20
- 全文大小：24K
- ISSN：1522-2667
文摘
An efficient, one-pot, three-component procedure for the synthesis of fluorinated oxazinoisoquinolines with excellent regioselectivity and diastereoselectivity is presented.