Synthesis and in vitro evaluation of pH-sensitive PEG-I-dC16 block polymer micelles for anticancer drug delivery
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- 作者：Huang Rongbin ; Xiang Lei ; Liu Ying ; Deng Xiangping ; Cao Xuan ; Li Lanfang ; Yu Cuiyun ; Chen Yanming and Tang Guotao
- 刊名：Journal of Pharmacy and Pharmacology
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：68
- 期：6
- 页码：751-761
- 全文大小：1891K
- ISSN：2042-7158
文摘
To develop an acid trigger release of antitumour drug delivery carriers, pH-sensitive amphiphilic poly (ethyleneglycol)-imine-benzoic-dipalmitate (PEG-I-dC16) polymers were designed and synthesized and the drug-loaded micelles were evaluated in vitro.