Two New Triterpenoid Glycosides from the Roots of Rosa cymosa Tratt.
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- 作者：Guo-Xu Ma ; Xiao-Yan Huang ; Hua-Nian Dai ; Xiao-Qing Zhong ; Yan-Lin Zhou ; Zuo-Lin Su ; Ying-Zi He ; Jun-Shan Yang ; Jing-Quan Yuan and Xu-Dong Xu
- 刊名：Helvetica Chimica Acta
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：99
- 期：6
- 页码：482-486
- 全文大小：82K
- ISSN：1522-2675
文摘
Two new triterpenoid glycosides, 3α,19α,23α-trihydroxy-2-oxo-12-ursen-28-O-β-d-glucopyranoside (1) and 3α,19α,23α-trihydroxy-2-oxoolean-12-en-28-O-β-d-glucopyranoside (2) as well as three known compounds, 2α,3α,19α-trihydroxyolean-12-en-28-O-β-d-glucopyranoside (3), 2α,3α,19α,23-tetrahydroxy-12-ursen-28-O-β-d-glucopyranoside (4), and 2α,3β,19α,23-tetrahydroxyurs-12-en-28-oic acid (5) were isolated from 75% EtOH extract of Rosa cymosa. Their structures were elucidated by extensive spectroscopic methods. All the isolated compounds displayed moderate inhibitory activity against LPS-induced NO production in macrophages.