Cover Picture: Asymmetric Catalytic Aza-Diels-Alder/Ring-Closing Cascade Reaction Forming Bicyclic Azaheterocycles by Trienamine Catalysis (Chem. Eur. J. 1/2017)

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• 作者：Yang Li ; Casper Barlø ; se ; Julie Jø ; rgensen ; Bjø ; rn Dreiø ; Carlsen and Prof. Dr. Karl Anker Jø ; rgensen
• 刊名：Chemistry - A European Journal
• 出版年：2017
• 出版时间：January 1, 2017
• 年：2017
• 卷：23
• 期：1
• 页码：1
• 全文大小：368K
• ISSN：1521-3765

文摘

This artwork presents the basic reaction concept of the asymmetric catalytic aza-Diels–Alder/ring-closing cascade by the operation mode of a zipper. The two molecules (red: 2,4-dienal; blue: hydrazone) in this reaction are mosaicked into the two chains of the zipper. The chiral slider, the diarylprolinol-silyl ether catalyst, zips together the two molecules by sliding the hand down the chains forming the bicyclic aza-heterocyclic products in a highly stereoselective manner. More information can be found in the Communication by K. A. Jørgensen et al. on page 38 ff.