Polymer Nanoparticles: Multifunctional Conjugated Polymer Nanoparticles for Image-Guided Photodynamic and Photothermal Therapy (Small 3/2017)

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• 作者：Guangxue Feng ; Yuan Fang ; Jie Liu ; Junlong Geng ; Dan Ding and Bin Liu
• 刊名：Small
• 出版年：2017
• 出版时间：January 18, 2017
• 年：2017
• 卷：13
• 期：3
• 全文大小：2108K
• ISSN：1613-6829

文摘

Multifunctional conjugated polymer nanoparticles (CPNs) are developed for image-guided phototherapy by D. Ding, B. Liu, and co-workers in article number 1602807. Under proper light irradiation, these CPNs display bright red fluorescence, efficient singlet oxygen generation and excellent photothermal conversion abilities. With affibody decoration, these CPNs show excellent tumor targeting and synergistic therapeutic efficacy through the cooperation of photodynamic and photothermal therapy both in vitro and in vivo.