KIO₃-Catalyzed Domino C(sp²)−H Bond Sulfenylation and C−N Bond Oxygenation of Enaminones toward the Synthesis of 3-Sulfenylated Chromones

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• 作者：Shanshan Zhong ; Prof. Dr. Yunyun Liu ; Prof. Dr. Xiaoji Cao and Prof. Dr. Jie-Ping Wan
• 刊名：ChemCatChem
• 出版年：2017
• 出版时间：February 6, 2017
• 年：2017
• 卷：9
• 期：3
• 页码：465-468
• 全文大小：431K
• ISSN：1867-3899

文摘

With 2-hydroxyphenyl-functionalized enaminones and thiophenols as the starting materials, the facile synthesis of 3-sulfenylated chromones has been realized through a KIO₃-catalyzed domino reaction of C−H sulfenylation and subsequent C−N-cleavage-based C−O bond formation. The reaction was performed under transition-metal-free conditions in ethyl lactate, a bioavailable ecofriendly medium.