Convenient Construction of Indanedione-Fused 2,5-Dihydropyridines, 4,5-Dihydropyridines, and Spirooxindolines

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• 作者：Wen-Juan Yang ; Jing Zhang ; Jing Sun and Chao-Guo Yan
• 刊名：European Journal of Organic Chemistry
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：2016
• 期：32
• 页码：5423-5428
• 全文大小：841K
• ISSN：1099-0690

文摘

A cycloaddition reaction promoted by the Lewis acid BF₃·OEt₂ between 2-arylidene-1,3-indanediones and β-enamino esters, generated by the addition of arylamines to dimethyl acetylenedicarboxylate, gave densely substituted 1,4-diphenyl-4,5-dihydro-1H-indeno[1,2-b]pyridines in satisfactory yields. When 2-isatylidene-1,3-indanediones were used under the same conditions, the one-pot reaction gave the corresponding spiro[indeno[1,2-b]pyridine-4,3′-indolines] in high yields. On the other hand, unusual 1,2-diphenyl-2,5-dihydro-1H-indeno[1,2-b]pyridines were obtained in moderate to good yields through a four-component reaction.