Synthesis of homoallylic amines and acylhydrazides by tin powder-promoted multicomponent one-pot allylation reactions

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• 作者：Junyan Ma ; Danfeng Huang ; Ke-Hu Wang ; Yanli Xu ; Siying Chong ; Yingpeng Su ; Ying Fu and Yulai Hu
• 刊名：Applied Organometallic Chemistry
• 出版年：2016
• 出版时间：July 2016
• 年：2016
• 卷：30
• 期：7
• 页码：571-576
• 全文大小：758K
• ISSN：1099-0739

文摘

An efficient process for the synthesis of homoallylic amines and N′-homoallylic hydrazides is developed from the one-pot reaction of carbonyl compounds, amines or N-acylhydrazines, allyllic bromide and tin powder using water as solvent. N-Acylhydrazines are found to be more reactive than amines in these processes. They can react not only with aldehydes but also with ketones to give the corresponding N′-homoallylic hydrazides. Copyright