Salivary pathogen and serum antibody to assess the progression of chronic periodontitis: a 24-mo prospective multicenter cohort study
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- 作者：T. Morozumi ; T. Nakagawa ; Y. Nomura ; T. Sugaya ; M. Kawanami ; F. Suzuki ; K. Takahashi ; Y. Abe ; S. Sato ; A. Makino-Oi ; A. Saito ; S. Takano ; M. Minabe ; Y. Nakayama ; Y. Ogata ; H. Kobayashi ; Y. Izumi ; N. Sugano ; K. Ito ; S. Sekino ; Y. Numabe ; C. Fukaya ; N. Yoshinari ; M. Fukuda ; T. Noguchi ; T. Kono ; M. Umeda ; O. Fujise ; F. Nishimura ; A. Yoshimura ; Y. Hara ; T. Nakamura ; K. Noguchi ; E. Kakuta ; N. Hanada ; S. Takashiba and H. Yoshie
- 刊名：Journal of Periodontal Research
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：51
- 期：6
- 页码：768-778
- 全文大小：179K
- ISSN：1600-0765
文摘
A diagnosis of periodontitis progression is presently limited to clinical parameters such as attachment loss and radiographic imaging. The aim of this multicenter study was to monitor disease progression in patients with chronic periodontitis during a 24-mo follow-up program and to evaluate the amount of bacteria in saliva and corresponding IgG titers in serum for determining the diagnostic usefulness of each in indicating disease progression and stability.