Cytotoxic potential of IL-15-activated cytokine-induced killer cells against human neuroblastoma cells
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- 作者：Claudia Cappel ; Sabine Huenecke ; Anica Suemmerer ; Stephanie Erben ; Eva Rettinger ; Verena Pfirrmann ; Annekathrin Heinze ; Olga Zimmermann ; Thomas Klingebiel ; Evelyn Ullrich ; Peter Bader and Melanie Bremm
- 刊名：Pediatric Blood & Cancer
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：63
- 期：12
- 页码：2230-2239
- 全文大小：1595K
- ISSN：1545-5017
文摘
Neuroblastoma (NB) is the most common solid extracranial tumor in childhood. Despite advances in therapy, the prognosis is poor and optimized therapies are urgently needed. Therefore, we investigated the antitumor potential of interleukin-15 (IL-15)-activated cytokine-induced killer (CIK) cells against different NB cell lines.