Optical Modulation of Azobenzene-Modified Peptide for Gold Surface Binding

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• 作者：Dr. Joseph M. Slocik ; Dr. Zhifeng Kuang ; Prof. Marc R. Knecht and Dr. Rajesh R. Naik
• 刊名：ChemPhysChem
• 出版年：2016
• 出版时间：October 18, 2016
• 年：2016
• 卷：17
• 期：20
• 页码：3252-3259
• 全文大小：2537K
• ISSN：1439-7641

文摘

The ability to precisely and remotely modulate reversible binding interactions between biomolecules and abiotic surfaces is appealing for many applications. To achieve this level of control, an azobenzene-based optical switch is added to nanoparticle-binding peptides in order to switch peptide conformation and attenuate binding affinity to gold surfaces via binding and dissociation of peptides.