ChemInform Abstract: Efficient Synthesis of Chiral Trisubstituted 1,2-Allenyl Ketones by Catalytic Asymmetric Conjugate Addition of Malonic Esters to Enynes.

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• 作者：Qian Yao ; Yuting Liao ; Lili Lin ; Xiaobin Lin ; Jie Ji ; Xiaohua Liu and Xiaoming Feng
• 刊名：ChemInform
• 出版年：2016
• 出版时间：May, 2016
• 年：2016
• 卷：47
• 期：22
• 全文大小：32K
• ISSN：1522-2667

文摘

The conjugate addition of malonic esters to enynes in the presence of a scandium(III)/N,N-dioxide complex yields a range of trisubstituted allenyl ketones with good diastereomeric ratios and excellent e.e.-values.