Injectable thiol-epoxy “click” hydrogels
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- 作者：Lilong Gao ; Xiaojun Li ; Ying Wang ; Weipu Zhu ; Zhiquan Shen and Xiaodong Li
- 刊名：Journal of Polymer Science Part A: Polymer Chemistry
- 出版年：2016
- 出版时间：1 September 2016
- 年：2016
- 卷：54
- 期：17
- 页码：2651-2655
- 全文大小：500K
- ISSN：1099-0518
文摘
A novel crosslinking strategy for injectable “click” hydrogels is reported. Precursors containing thiol or epoxy groups are facilely synthesized by polycondensation and radical polymerization respectively, which are used to in situ form hydrogels under physiological conditions within tens of seconds via thiol-epoxy reaction. The suitable gelation time and low cytotoxicity of this kind of hydrogels make it a potential candidate as implanted material for biomedical applications.