Simtuzumab treatment of advanced liver fibrosis in HIV and HCV-infected adults: results of a 6-month open-label safety trial
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- 作者：Eric G. Meissner ; Mary McLaughlin ; Lindsay Matthews ; Ahmed M. Gharib ; Bradford J. Wood ; Elliot Levy ; Ralph Sinkus ; Kimmo Virtaneva ; Dan Sturdevant ; Craig Martens ; Stephen F. Porcella ; Zachary D. Goodman ; Bittoo Kanwar ; Robert P. Myers ; Mani Subramanian ; Colleen Hadigan ; Henry Masur ; David E. Kleiner ; Theo Heller ; Shyam Kottilil ; Joseph A. Kovacs and Caryn G. Morse
- 刊名：Liver International
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：36
- 期：12
- 页码：1783-1792
- 全文大小：463K
- ISSN：1478-3231
文摘
Chronic liver injury can result in fibrosis that may progress over years to end-stage liver disease. The most effective anti-fibrotic therapy is treatment of the underlying disease, however when not possible, interventions to reverse or slow fibrosis progression are needed.