Combination treatment with fingolimod and a pathogenic antigen prevents relapse of glucose-6-phosphate isomerase peptide-induced arthritis

详细信息    查看全文

• 作者：Yuya Yoshida ; Norihisa Mikami ; Yuki Matsushima ; Mai Miyawaki ; Hiroki Endo ; Rie Banno ; Takumi Tsuji ; Tetsuro Fujita and Takeyuki Kohno
• 刊名：Immunity, Inflammation and Disease
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：4
• 期：3
• 页码：263-273
• 全文大小：979K
• ISSN：2050-4527

文摘

Combination treatment with fingolimod (FTY720) plus pathogenic antigen is thought to prevent glucose-6-phosphate isomerase (GPI)_325-339-induced arthritis progression by effective induction of immune tolerance. Here, we examined the efficacy of this combination treatment on remission maintenance.