A Simple, Rapid, and Highly Sensitive Electrochemical DNA Sensor for the Detection of α- and β-Thalassemia in China

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• 作者：Pei-Qi Chen ; Qian-Ni Liang ; Tao-Sheng Huang ; Tian-Cai Liu and Ming Li
• 刊名：Journal of Clinical Laboratory Analysis
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：30
• 期：5
• 页码：719-726
• 全文大小：2229K
• ISSN：1098-2825

文摘

Because of the life-consuming treatment and severe consequences associated with thalassemia, it is more effective to prevent than cure thalassemia. Rapid and sensitive detection is critical for controlling thalassemia. In this study, we developed a rapid and accurate test to genotype nondeletional α- and β-thalassemia mutations by an electrochemical DNA sensor.