A series of novel 10-substituted 3,6-diphenyl-9-aryl-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione derivatives
were synthesi
zed by condensation of compounds
with amines, which the compounds
were synthesi
zed by
5-phenylcyclohexane-1,3-dione and aromatic aldehydes according to Knoevenagel, Michael, and
cyclization reactions in the presence of a very small amount of
l-proline as cataly
zed at room temperature. The structures of all the synthesi
zed compounds were characteri
zed by IR, 1H NMR, and MS. In addition, the molecular structures of compound
have been determined by single-crystal X-ray diffraction analysis.