General and Direct Synthesis of Indolizine-1-carbaldehydes by 1,3-Dipolar Cycloaddition of Phenylpropiolaldehyde with Pyridinium Ylides

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• 作者：Tao Gao ; Xiuling Chen ; Longqiang Jiang ; Minghu Wu ; Haibing Guo ; Jian Wang ; Shaofa Sun ; Jeremy Oiler and Yalan Xing
• 刊名：European Journal of Organic Chemistry
• 出版年：2016
• 出版时间：October 2016
• 年：2016
• 卷：2016
• 期：29
• 页码：4957-4960
• 全文大小：669K
• ISSN：1099-0690

文摘

An efficient and one-step synthesis of indolizine-1-carbaldehydes from phenylpropiolaldehyde and pyridinium ylides was developed. The elegant methodology afforded functionalized indolizines with easy operation under mild reaction conditions and with wide substrate scope.