Safety of contralateral submandibular gland sparing in locally advanced oropharyngeal cancers: A multicenter review
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- 作者：Tyler P. Robin ; Gregory N. Gan ; Moses Tam ; David Westerly ; Nadeem Riaz ; Sana D. Karam ; Nancy Lee and David Raben
- 关键词：head and neck cancer ; submandibular gland ; xerostomia ; intensity-modulated radiation therapy (IMRT) ; salivary glands
- 刊名：Head & Neck
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：38
- 期：4
- 页码：506-511
- 全文大小：178K
- ISSN：1097-0347
文摘
Previous groups have shown contralateral submandibular gland sparing to improve xerostomia with safe outcomes, but primarily in early-stage disease. In this study, we present a large cohort of patients with locally advanced head and neck cancer that underwent contralateral submandibular gland-sparing radiotherapy, to demonstrate feasibility and safety specifically in patients with locally advanced disease.