Biochanin A improves hepatic steatosis and insulin resistance by regulating the hepatic lipid and glucose metabolic pathways in diet-induced obese mice
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- 作者：Hee-Sook Park ; Haeng Jeon Hur ; Soon-Hee Kim ; Su-Jin Park ; Moon Ju Hong ; Mi Jeong Sung ; Dae Young Kwon and Myung-Sunny Kim
- 刊名：Molecular Nutrition & Food Research
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：60
- 期：9
- 页码：1944-1955
- 全文大小：1602K
- ISSN：1613-4133
文摘
Natural compounds that regulate peroxisome proliferator-activated receptor alpha (PPARα) have been reported to have beneficial effects in obesity-mediated metabolic disorders. In this study, we demonstrated that biochanin A (BA), an agonist of PPAR-α, improved hepatic steatosis and insulin resistance by regulating hepatic lipid and glucose metabolism.