Young Investigator Challenge: Molecular testing in noninvasive follicular thyroid neoplasm with papillary-like nuclear features

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• 作者：Xiaoyin &ldquo ; Sara&rdquo ; Jiang ; Grant P. Harrison and Michael B. Datto
• 刊名：Cancer Cytopathology
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：124
• 期：12
• 页码：893-900
• 全文大小：544K
• ISSN：1934-6638

文摘

Molecular testing provides an important ancillary study for thyroid nodules with indeterminate cytology. The nomenclature shift to “noninvasive follicular thyroid neoplasm with papillary-like nuclear features” (NIFTP) will impact the performance of molecular tests. For the current study, the authors reviewed the performance of the Afirma gene-expression classifier (GEC) and the University of Pittsburgh Medical Center (UPMC) targeted mutation panel tests in thyroid nodules that were subsequently diagnosed as NIFTP on surgical resection.