Between- and within-site variability of fMRI localizations
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- 作者：Jakob Rath ; Moritz Wurnig ; Florian Fischmeister ; Nicolaus Klinger ; Ilse Hö ; llinger ; Alexander Geiß ; ler ; Markus Aichhorn ; Thomas Foki ; Martin Kronbichler ; Janpeter Nickel ; Christian Siedentopf ; Wolfgang Staffen ; Michael Verius ; Stefan Golaszewski ; Florian Koppelstaetter ; Eduard Auff ; Stephan Felber ; Rü ; diger J. Seitz and Roland Beisteiner
- 刊名：Human Brain Mapping
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：37
- 期：6
- 页码：2151-2160
- 全文大小：194K
- ISSN：1097-0193
文摘
This study provides first data about the spatial variability of fMRI sensorimotor localizations when investigating the same subjects at different fMRI sites. Results are comparable to a previous patient study. We found a median between-site variability of about 6 mm independent of task (motor or sensory) and experimental standardization (high or low). An intraclass correlation coefficient analysis using data quality measures indicated a major influence of the fMRI site on variability. In accordance with this, within-site localization variability was considerably lower (about 3 mm). We conclude that the fMRI site is a considerable confound for localization of brain activity. However, when performed by experienced clinical fMRI experts, brain pathology does not seem to have a relevant impact on the reliability of fMRI localizations. Hum Brain Mapp 37:2151–2160, 2016.