External-beam radiotherapy for differentiated thyroid cancer locoregional control: A statement of the American Head and Neck Society

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• 作者：Ana P. Kiess ; Nishant Agrawal ; James D. Brierley ; Umamaheswar Duvvuri ; Robert L. Ferris ; Eric Genden ; Richard J. Wong ; R. Michael Tuttle ; Nancy Y. Lee and Gregory W. Randolph
• 关键词：radiotherapy ; radiation ; thyroid cancer ; papillary ; follicular
• 刊名：Head & Neck
• 出版年：2016
• 出版时间：April 2016
• 年：2016
• 卷：38
• 期：4
• 页码：493-498
• 全文大小：102K
• ISSN：1097-0347

文摘

The use of external-beam radiotherapy (EBRT) in differentiated thyroid cancer (DTC) is debated because of a lack of prospective clinical data, but recent retrospective studies have reported benefits in selected patients. The Endocrine Surgery Committee of the American Head and Neck Society provides 4 recommendations regarding EBRT for locoregional control in DTC, based on review of literature and expert opinion of the authors. (1) EBRT is recommended for patients with gross residual or unresectable locoregional disease, except for patients <45 years old with limited gross disease that is radioactive iodine (RAI)-avid. (2) EBRT should not be routinely used as adjuvant therapy after complete resection of gross disease. (3) After complete resection, EBRT may be considered in select patients >45 years old with high likelihood of microscopic residual disease and low likelihood of responding to RAI. (4) Cervical lymph node involvement alone should not be an indication for adjuvant EBRT.