Quantitative MRI biomarkers to characterize regional left ventricular perfusion and function in nonhuman primates during dobutamine-induced stress: A reproducibility and reliability study
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- 作者：Smita Sampath ; Annamalai Sarayu Parimal ; Dai Feng ; Miko May Lee Chang ; Richard Baumgartner ; Michael Klimas ; Kirsten Jacobsen ; Elaine Manigbas ; Willy Gsell ; Jeffrey L. Evelhoch and Chih-Liang Chin
- 刊名：Journal of Magnetic Resonance Imaging
- 出版年：2017
- 出版时间：February, 2017
- 年：2017
- 卷：45
- 期：2
- 页码：556-569
- 全文大小：862K
- ISSN：1522-2586
文摘
To identify reproducible and reliable noninvasive regional imaging biomarkers of cardiac function and perfusion at rest and under stress in healthy nonhuman primates (NHPs) that may be used in the future for the early characterization of preclinical heart failure models, to evaluate therapy, and for clinical translation.