An improved anatomical MRI technique with suppression of fixative fluid artifacts for the investigation of human postmortem brain phantoms
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- 作者：Amgad Droby ; Kenneth Sung Lai Yuen ; Anne Schä ; nzer ; Isabella Spiwoks-Becker ; Till Acker ; Bianca Lienerth ; Frauke Zipp and Ralf Deichmann
- 刊名：Magnetic Resonance in Medicine
- 出版年：2017
- 出版时间：March 2017
- 年：2017
- 卷：77
- 期：3
- 页码：1115-1123
- 全文大小：5612K
- ISSN：1522-2594
文摘
Phantoms are often used to assess MR system stability in multicenter studies. Postmortem brain phantoms best replicate human brain anatomy, allowing for a combined assessment of the MR system and software chain for data analysis. However, a wash-out of fixative fluid affecting T1 values and thus T1-weighted sequences such as magnetization-prepared 180 degrees radiofrequency pulses and rapid gradient-echo (MP-RAGE) has been reported for brain phantoms, hampering their immediate use. The purpose of this study was the creation of anatomical data that provide the characteristics of conventional data while avoiding this artifact.