Bacterial vaginosis: a critical analysis of current knowledge

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• 作者：D Nasioudis ; IM Linhares ; WJ Ledger ; SS Witkin
• 刊名：BJOG: An International Journal of Obstetrics & Gynaecology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：124
• 期：1
• 页码：61-69
• 全文大小：221.4KB
• ISSN：1471-0528

文摘

Bacterial vaginosis (BV), the change from a Lactobacillus-dominant vaginal microbiota to an anaerobic and facultative bacterial dominance, is associated with pathological sequelae. In many BV-positive women their microbiota is in fact normal and unrelated to pathology. Whether or not the dominance of BV-associated bacteria persists depends upon interactions between host and bacterial factors. Inconsistencies in diagnosis and erroneous associations with pathology may be due to a failure to differentiate between sub-populations of women. It is only in those women with a BV diagnosis in which the identified bacteria are atypical and persist that BV may be a clinical problem requiring intervention.