Estimating vaccine effectiveness in preventing laboratory-confirmed influenza in outpatient settings in South Africa, 2015

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• 作者：Johanna M. McAnerney ; Sibongile Walaza ; Stefano Tempia ; Lucille Blumberg ; Florette K. Treurnicht ; Shabir A. Madhi ; Ziyaad Valley-Omar and Cheryl Cohen
• 刊名：Influenza and Other Respiratory Viruses
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：11
• 期：2
• 页码：177-181
• 全文大小：320K
• ISSN：1750-2659

文摘

Trivalent seasonal influenza vaccine effectiveness during the 2015 season in South Africa was assessed using a test-negative case control study design. Influenza A(H1N1)pdm09 was the dominant circulating strain. Overall influenza vaccine coverage was 3.2% (29/899). The vaccine effectiveness estimate, against any influenza virus infection, adjusted for age, underlying conditions and timing within season was 46.2% (95% CI: −23.5 to 76.5), and 53.6% (95% CI: −62.6 to 80.3) against influenza A(H1N1)pdm09.