Front Cover: 1-Hydrosilatrane: A Locomotive for Efficient Ketone Reductions (Eur. J. Org. Chem. 2/2017)
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- 作者：Sami E. Varjosaari ; Vladislav Skrypai ; Paolo Suating ; Joseph J. M. Hurley ; Thomas M. Gilbert and Marc J. Adler
- 刊名：European Journal of Organic Chemistry
- 出版年：2017
- 出版时间：January 10, 2017
- 年：2017
- 卷：2017
- 期：2
- 页码：208
- 全文大小：3416K
- ISSN：1099-0690
文摘
The cover picture shows artist Jesse Mai's imagination of the reduction of ketones to alcohols by 1-hydrosilatrane. The accompanying work describes this mild method for reduction, which makes use of a cheap, safe, easy-to-handle, and environmentally friendly silane reducing reagent. The reported results include the conversion of a wide scope of ketones to alcohols, as well as demonstrations of stereoselective reductions: the diastereoselective reduction of (–)-menthone to (+)-neomenthol and the reduction of a prochiral ketone to an alcohol with an enantiomeric ratio of 87:13. Details are discussed in the Communication by M. J. Adler et al. on page 229 ff (DOI: m/doi/10.1002/ejoc.201601256/abstract" title="Link to external resource: http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201601256/abstract" target="_blank">10.1002/ejoc.201601256).