Red selenium nanoparticles and gray selenium nanorods as antibacterial coatings for PEEK medical devices
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- 作者：Qi Wang ; Alejandra Mejí ; a Jaramillo ; Juan J. Pavon and Thomas J. Webster
- 刊名：Journal of Biomedical Materials Research Part B: Applied Biomaterials
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：104
- 期：7
- 页码：1352-1358
- 全文大小：408K
- ISSN：1552-4981
文摘
Bacterial infections are commonly found on various poly(ether ether ketone) (PEEK) medical devices (such as orthopedic instruments, spinal fusion devices, and segments in dialysis equipment), and thus, there is a significant need for introducing antibacterial properties to such materials. The objective of this in vitro study was to introduce antibacterial properties to PEEK medical devices by coating them with nanosized selenium. In this study, red selenium (an elemental form of selenium) nanoparticles were coated on PEEK medical devices through a quick precipitation method. Furthermore, with heat treatment at 100°C for 6 days, red selenium nanoparticles were transferred into gray selenium nanorods on the PEEK surfaces. Bacteria test results showed that both red and gray selenium-coated PEEK medical devices significantly inhibited the growth of Pseudomonas aeruginosa compared with uncoated PEEK after either 1, 2, or 3 days. Red selenium nanoparticle-coated PEEK showed less bacteria growth on its surface than gray selenium nanorod-coated PEEK after 3 days. This study demonstrated that red, and to a lesser extent gray, nanosized selenium could be used as potential antibacterial coatings to prevent bacteria function on PEEK medical devices.