Second malignancy risk among pediatric, adolescent, and young adult survivors of fusion-positive and fusion-negative sarcomas: Results from the SEER database, 1992 through 2012

详细信息    查看全文

• 作者：Philip J. Lupo ; Austin L. Brown and Simone Hettmer
• 刊名：Cancer
• 出版年：2016
• 出版时间：November 15, 2016
• 年：2016
• 卷：122
• 期：22
• 页码：3492-3500
• 全文大小：262K
• ISSN：1097-0142

文摘

The current study builds on the hypothesis that cancer-predisposing germline mutations are less common among patients with fusion-positive (F+) sarcomas compared to those with fusion-negative (F-) sarcomas, resulting in a lower risk of developing second malignant neoplasms (SMNs) in those with F + sarcomas.