Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans
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- 作者：Christopher J. Lessard ; Satria Sajuthi ; Jian Zhao ; Kwangwoo Kim ; John A. Ice ; He Li ; Hannah Ainsworth ; Astrid Rasmussen ; Jennifer A. Kelly ; Miranda Marion ; So-Young Bang ; Young Bin Joo ; Jeongim Choi ; Hye-Soon Lee ; Young Mo Kang ; Chang-Hee Suh ; Won Tae Chung ; Soo-Kon Lee ; Jung-Yoon Choe ; Seung Cheol Shim ; Ji Hee Oh ; Young Jin Kim ; Bok-Ghee Han ; Nan Shen ; Hwee Siew Howe ; Edward K. Wakeland ; Quan-Zhen Li ; Yeong Wook Song ; Patrick M. Gaffney ; Marta E. Alarcó ; n-Riquelme ; Lindsey A. Criswell ; Chaim O. Jacob ; Robert P. Kimberly ; Timothy J. Vyse ; John B. Harley ; Kathy L. Sivils ; Sang-Cheol Bae ; Carl D. Langefeld and Betty P. Tsao
- 刊名：Arthritis & Rheumatism
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：68
- 期：5
- 页码：1197-1209
- 全文大小：305K
- ISSN：1529-0131
文摘
Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder whose etiology is incompletely understood, but likely involves environmental triggers in genetically susceptible individuals. Using an unbiased genome-wide association (GWA) scan and replication analysis, we sought to identify the genetic loci associated with SLE in a Korean population.