Chiral Recognition of Tryptophan Enantiomers Based on β-Cyclodextrin-platinum Nanoparticles/Graphene Nanohybrids Modified Electrode
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- 作者：Juanjuan Xu ; Qinghong Wang ; Chunzhi Xuan ; Qiao Xia ; Xia Lin and Yingzi Fu
- 关键词：Chiral recognition ; Nanohybrids ; Tryptophan enantiomers ; Electrochemical methods
- 刊名：Electroanalysis
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：28
- 期：4
- 页码：868-873
- 全文大小：1117K
- ISSN：1521-4109
文摘
The nanohybrids which based on β-cyclodextrin, platinum nanoparticles and graphene (β-CD-PtNPs/GNs) were successfully synthesized and characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), fourier transform infrared spectroscopy (FT-IR) and electrochemical impedance spectroscopy (EIS). Then they were used to construct a simple and reliable chiral sensing platform to interact with tryptophan (Trp) enantiomers. Differential pulse voltammetry (DPV) was used to investigate the stereo selectivity of β-CD-PtNPs/GNs to Trp enantiomers. After interaction, the obvious difference of peak currents of L-Trp and D-Trp was obtained, indicating this strategy could be employed to chiral recognition of Trp enantiomers. Under the optimum conditions, the chiral sensor exhibited a good linear response to Trp enantiomers in a linear range of 5.0×10−5 to 5.0×10−3 M with a low limit of detection of 1.7×10−5 M (S/N=3). This approach provided a new available platform to recognize and determine Trp enantiomers.