Transition-Metal-Catalyzed Transformations of 1-Alkenylpropargyl Alcohols and Esters: Valuable Cascade Reactions for Increasing Structural Complexity
详细信息 查看全文
- 作者：Edgar Haak
- 刊名：European Journal of Organic Chemistry
- 出版年：2017
- 出版时间：February 03, 2017
- 年：2017
- 卷：2017
- 期：5
- 页码：940-949
- 全文大小：2075K
- ISSN：1099-0690
文摘
It is the aim of this microreview to highlight the diversity of structural conversions that are accessible from 1-alkenylpropargyl alcohols and esters in the context of transition-metal-catalyzed cascade transformations. These readily available enynols facilitate diverse transition-metal-catalyzed cascade reactions, exploiting their different functional sites. This C5 motif thus represents a set of common precursors for a broad range of structurally very diverse scaffolds, making its cascade transformations valuable tools in organic synthesis and drug discovery.