The New Prostate Cancer Grading System Does Not Improve Prediction of Clinical Recurrence After Radical Prostatectomy: Results of a Large, Two-Center Validation Study
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- 作者：Paolo Dell'Oglio ; Robert Jeffrey Karnes ; Giorgio Gandaglia ; Nicola Fossati ; Armando Stabile ; Marco Moschini ; Vito Cucchiara ; Emanuele Zaffuto ; Pierre I. Karakiewicz ; Nazareno Suardi ; Francesco Montorsi and Alberto Briganti
- 刊名：The Prostate
- 出版年：2017
- 出版时间：February 15, 2017
- 年：2017
- 卷：77
- 期：3
- 页码：263-273
- 全文大小：1089K
- ISSN：1097-0045
文摘
A new prostate cancer (PCa) grading system (namely, Gleason score-GS- ≤6 vs. 3 + 4 vs. 4 + 3 vs. 8 vs. ≥9) was recently proposed and assessed on biochemical recurrence (BCR) showing improved predictive abilities compared to the commonly used three-tier system (GS ≤6 vs. 7 vs. ≥8). We assessed the predictive ability of the five-tier grade group (GG) system on harder clinical endpoint, namely clinical recurrence (CR).