Treatment of Ribonucleoside Solution With Atmospheric-Pressure Plasma
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- 作者：Xianhui Zhang ; Renwu Zhou ; Rusen Zhou ; Maodong Chen ; Jiangwei Li ; Yue Sun ; Qiang Chen ; Size Yang and Qing Huo Liu
- 关键词：adenosine(Ado) oxidization ; deoxyadenosine(dA) ; electrospray tandem mass spectrometry (ESI-MS) ; microplasma ; online ion-pair reversed-phase liquid chromatography (IP-RPLC)
- 刊名：Plasma Processes and Polymers
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：13
- 期：4
- 页码：429-437
- 全文大小：2209K
- ISSN：1612-8869
文摘
A self-made microplasma jet array device is used to treat deoxyadenosine (dA) and adenosine (Ado) solutions to avoid the effect of air on genetic materials. Results show that Ado is easily converted into dA through deoxidation reaction. In addition, dA solution is treated with different microplasma arrays (i.e., atmospheric-pressure Ar, N2, air, and O2) for comparative analysis. The dA molecule is relatively stable within the Ar plasma for 3 min treatment time. This molecule can be modified into different structures with N2, air, and O2 microplasma arrays. The results obtained in this study provide references for the application of plasma in biology and the effect of oxygen-containing free radicals in biological plasma.