Pain-processing abnormalities in bipolar I disorder, bipolar II disorder, and schizophrenia: A novel trait marker for psychosis proneness and functional outcome?
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- 作者：Amedeo Minichino ; Roberto Delle Chiaie ; Giorgio Cruccu ; Serena Piroso ; Giulia Di Stefano ; Marta Francesconi ; Francesco Saverio Bersani ; Massimo Biondi and Andrea Truini
- 刊名：Bipolar Disorders
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：18
- 期：7
- 页码：591-601
- 全文大小：432K
- ISSN：1399-5618
文摘
Overlapping neural system dysfunctions, mainly involving the secondary somatosensory cortex (S2), the anterior cingulate cortex (ACC) and the anterior insular cortex (AIC), seem to be related to both pain-perception abnormalities and psychotic symptoms in schizophrenia (SCZ) and bipolar disorder (BD). Laser-evoked potentials (LEPs) were used to investigate pain-perception and central pain-processing abnormalities in SCZ, bipolar I disorder (BD-I), and bipolar II disorder (BD-II), and to evaluate their relationship with history of psychosis, and social-cognitive and functional impairments.