Propolis modulates miRNAs involved in TLR-4 pathway, NF-κB activation, cytokine production and in the bactericidal activity of human dendritic cells
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- 作者：Bruno J. Conti ; Karina B. Santiago ; Eliza O. Cardoso ; Paula P. Freire ; Robson F. Carvalho ; Marjorie A. Golim and José ; M. Sforcin
- 刊名：Journal of Pharmacy and Pharmacology
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：68
- 期：12
- 页码：1604-1612
- 全文大小：408K
- ISSN：2042-7158
文摘
Dendritic cells (DCs) are antigen-presenting cells, essential for recognition and presentation of pathogens to T cells. Propolis, a resinous material produced by bees from various plants, exhibits numerous biological properties, highlighting its immunomodulatory action. Here, we assayed the effects of propolis on the maturation and function of human DCs.