Inside Cover: Asymmetric Total Synthesis of Propindilactone G, Part 1: Initial Attempts towards the Synthesis of Schiartanes (Chem. Asian J. 9/2016)

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• 作者：Dr. Ling-Ming Xu ; Dr. Lin You ; Dr. Zhen-Hua Shan ; Ruo-Cheng Yu ; Bo Zhang ; Yuan-He Li ; Ying Shi ; Prof. Dr. Jia-Hua Chen and Prof. Dr. Zhen Yang
• 刊名：Chemistry – An Asian Journal
• 出版年：2016
• 出版时间：May 6, 2016
• 年：2016
• 卷：11
• 期：9
• 页码：1295
• 全文大小：650K
• ISSN：1861-471X

文摘

A concise total synthesis of (+)-propindilactone G, a nortriterpenoid isolated from the stems of Schisandra propinqua var. propinqua, has been achieved for the first time. The key steps include an asymmetric Diels–Alder reaction, a Pauson–Khand reaction, a Pd-catalyzed reductive hydrogenolysis reaction, and an oxidative heterocoupling reaction. These reactions enabled the synthesis in only 20 steps. As a consequence of our synthetic studies, the structure of propindilactone G has been revised. More information can be found in their Full Papers on pages 1406, 1414, and 1425 by Zhen Yang and Jia-Hua Chen et al. in Issue 9, 2016 (DOI: 10.1002/asia.201600129, 10.1002/asia.201600130, 10.1002/asia.201600131.).