Study of the anti-JCV antibody levels in a Spanish multiple sclerosis cohort
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- 作者：Marí ; a I. Dominguez-Mozo ; Macarena Rus ; Jose L. Santiago ; Guillermo Izquierdo ; Ignacio Casanova ; Victoria Galan ; M. Angel Garcia-Martinez ; Ana M. Arias-Leal ; Marta Garcí ; a-Montojo ; Silvia Pé ; rez-Pé ; rez ; Rafael Arroyo and Roberto Alvarez-Lafuente
- 刊名：European Journal of Clinical Investigation
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：47
- 期：2
- 页码：158-166
- 全文大小：197K
- ISSN：1365-2362
文摘
One of the risk factor to develop progressive multifocal leukoencephalopathy (PML) among natalizumab-treated patients is the presence and high levels of anti-JCV antibodies. Our purpose was to test the association of different clinical and demographic variables with the presence and levels of anti-JCV antibodies in a Spanish cohort of patients with multiple sclerosis (MS) during natalizumab treatment.