Site-Selective C-H Amidation of Azobenzenes with Dioxazolones under Rhodium Catalysis
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- 作者：Neeraj Kumar Mishra ; Yongguk Oh ; Mijin Jeon ; Sangil Han ; Satyasheel Sharma ; Sang Hoon Han ; Sung Hee Um and In Su Kim
- 刊名：European Journal of Organic Chemistry
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：2016
- 期：29
- 页码：4976-4980
- 全文大小：1163K
- ISSN：1099-0690
文摘
The rhodium(III)-catalyzed amidation reaction of azobenzenes with dioxazolones is described. This strategy allows the facile and efficient construction of highly substituted ortho-amidated azobenzenes by direct C–H cleavage approach. A wide range of substrates, excellent levels of chemoselectivity as well as high functional-group tolerance were observed. In addition, this protocol was used to generate an array of ortho-amidated ketazines. Further synthetic transformation of amidated azobenzenes furnished a facile construction of benzimidazole and benzotriazole derivatives.