The ginger component 6-shogaol prevents TNF-α-induced barrier loss via inhibition of PI3K/Akt and NF-κB signaling

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• 作者：Julia Luettig ; Rita Rosenthal ; In-Fah M. Lee ; Susanne M. Krug and Jö ; rg D. Schulzke
• 刊名：Molecular Nutrition & Food Research
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：60
• 期：12
• 页码：2576-2586
• 全文大小：2122K
• ISSN：1613-4133

文摘

Anti-inflammatory properties of the ginger-derived pungent component 6-shogaol (6-SG) have been studied intensively in recent years. Purpose of this study was to characterize the influence of 6-SG on inflammation-related intestinal barrier dysfunction, especially its paracellular component.