Application of recombinant antigen 5 allergens from seven allergy-relevant Hymenoptera species in diagnostics
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- 作者：M. Schiener ; B. Eberlein ; C. Moreno-Aguilar ; G. Pietsch ; P. Serrano ; M. McIntyre ; L. Schwarze ; D. Russkamp ; T. Biedermann ; E. Spillner ; U. Darsow ; M. Ollert ; C. B. Schmidt-Weber and S. Blank
- 刊名：Allergy
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：72
- 期：1
- 页码：98-108
- 全文大小：824K
- ISSN：1398-9995
文摘
Hymenoptera stings can cause severe anaphylaxis in untreated venom-allergic patients. A correct diagnosis regarding the relevant species for immunotherapy is often hampered by clinically irrelevant cross-reactivity. In vespid venom allergy, cross-reactivity between venoms of different species can be a diagnostic challenge. To address immunological IgE cross-reactivity on molecular level, seven recombinant antigens 5 of the most important Vespoidea groups were assessed by different diagnostic setups.