Sendai viroplexes for epidermal growth factor receptor-directed delivery of interleukin-12 and salmosin genes to cancer cells
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- 作者：Jung Seok Kim ; Min Woo Kim ; Hwa Yeon Jeong ; Seong Jae Kang ; Sang Il Park ; Yeon Kyung Lee ; Hong Sung Kim ; Keun Sik Kim and Yong Serk Park
- 刊名：The Journal of Gene Medicine
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：18
- 期：7
- 页码：112-123
- 全文大小：627K
- ISSN：1521-2254
文摘
The effective delivery of therapeutic genes to target cells has been a fundamental goal in cancer gene therapy because of its advantages with respect to both safety and transfection efficiency. In the present, study we describe a tumor-directed gene delivery system that demonstrates remarkable efficacy in gene delivery and minimizes the off-target effects of gene transfection.