The effect of middle turbinate resection on topical drug distribution into the paranasal sinuses

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• 作者：Ashleigh A. Halderman ; Janalee Stokken and Raj Sindwani
• 刊名：International Forum of Allergy & Rhinology
• 出版年：2016
• 出版时间：October 2016
• 年：2016
• 卷：6
• 期：10
• 页码：1056-1061
• 全文大小：581K
• ISSN：2042-6984

文摘

During sinus surgery, partial or complete resection of the middle turbinate (MT) is sometimes necessary because of polypoid changes or demineralization. Topical drug delivery to the paranasal sinuses is an integral component in managing chronic rhinosinusitis (CRS) with and without nasal polyposis. The purpose of this study was to examine the role of the MT and MT resection in topical drug distribution into the sinuses via nebulization. We report on a novel technique of quantitatively evaluating the delivery of nebulized dye in cadavers.