“Cross-Dressing” Becomes Fashionable Among Transplant Recipients

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• 作者：W. J. Burlingham
• 刊名：American Journal of Transplantation
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：17
• 期：1
• 页码：5-6
• 全文大小：30K
• ISSN：1600-6143

文摘

Alloantigen “direct” presentation, once thought to be a transient phase mediated by cells that emigrate from the vascularized graft, re-emerges as the much more formidable and ongoing “semi-direct” pathway—driven not by donor cells per se but by their exosomes that “cross-dress” the surface of host APC with intact allo-MHC. See Smyth et al's article on ref="http://onlinelibrary.wiley.com/doi/10.1111/ajt.13996/abstract" rel="references:http://onlinelibrary.wiley.com/doi/10.1111/ajt.13996/abstract">page 60.