Muscle Biopsy Findings in Combination With Myositis-Specific Autoantibodies Aid Prediction of Outcomes in Juvenile Dermatomyositis
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- 作者：Claire T. Deakin ; Shireena A. Yasin ; Stefania Simou ; Katie A. Arnold ; Sarah L. Tansley ; Zoe E. Betteridge ; Neil J. McHugh ; Hemlata Varsani ; Janice L. Holton ; Thomas S. Jacques ; Clarissa A. Pilkington ; Kiran Nistala ; Lucy R. Wedderburn and on behalf of the UK Juvenile Dermatomyositis Research Group
- 刊名：Arthritis & Rheumatism
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：68
- 期：11
- 页码：2806-2816
- 全文大小：279K
- ISSN：1529-0131
文摘
Juvenile dermatomyositis (DM) is a rare and severe autoimmune condition characterized by rash and proximal muscle weakness. While some patients respond to standard treatment, others do not. This study was carried out to investigate whether histopathologic findings and myositis-specific autoantibodies (MSAs) have prognostic significance in juvenile DM.