Fibroblast growth factor family aberrations as a putative driver of head and neck squamous cell carcinoma in an epidemiologically low-risk patient as defined by targeted sequencing

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• 作者：Brittny N. Tillman ; Megan Yanik ; Andrew C. Birkeland ; Chia-Jen Liu ; Daniel H. Hovelson ; Andi K. Cani ; Nallasivam Palanisamy ; Shannon Carskadon ; Thomas E. Carey ; Carol R. Bradford ; Scott A. Tomlins ; Jonathan B. McHugh ; Matthew E. Spector and J. Chad Brenner
• 关键词：head and neck squamous cell carcinoma (HNSCC) ; fibroblast growth factor (FGF) ; fibroblast growth factor receptor (FGFR) ; amplification ; mutant
• 刊名：Head & Neck
• 出版年：2016
• 出版时间：April 2016
• 年：2016
• 卷：38
• 期：S1
• 页码：E1646-E1652
• 全文大小：2907K
• ISSN：1097-0347

文摘

Targeted sequencing of patients with epidemiologically low-risk (ELR) head and neck squamous cell carcinoma (HNSCC) could help identify novel drivers or lost suppressors leading to precision medicine protocols and improved survival rates.