Telomere length-related gene ACYP2 polymorphism is associated with the risk of HAPE in Chinese Han population
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- 作者：Yongjun He ; Xiyang Zhang ; Xun Li ; Jieli Du ; Xue He ; Zhiying Zhang ; Yuan Zhang ; Longli Kang ; Tianbo Jin and Dongya Yuan
- 刊名：The Journal of Gene Medicine
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：18
- 期：9
- 页码：244-249
- 全文大小：104K
- ISSN：1521-2254
文摘
High altitude pulmonary edema (HAPE) is a type of pneumonedema that mostly occurs under conditions such as high altitude, rapid ascent and hypoxia, amongst others. The ACYP2 polymorphism is suggested to be associated with mean telomere length, and telomere length is significantly longer at a moderate attitude than at sea-level or at simulated high attitude. The present study aimed to determine whethher there is any association between ACYP2 polymorphism and the risk of HAPE.